tag:blogger.com,1999:blog-18505975.post3188999133028707525..comments2023-09-08T01:52:01.330-07:00Comments on Economic Sense: TYPE II ERROR BIAS: THE FDAMatt Bogardhttp://www.blogger.com/profile/10510725993509264716noreply@blogger.comBlogger4125tag:blogger.com,1999:blog-18505975.post-8529846207679514942012-12-01T01:12:09.454-08:002012-12-01T01:12:09.454-08:00Dear Matt
Thank you for your explanation
It appea...Dear Matt<br /><br />Thank you for your explanation<br />It appears that the FDA is practising defensive medicine because of fear of litigation.<br /><br />If the end result is that potentially useful drugs are not reaching patients for this reason the system in which the FDA operates has to change<br /><br />For example maintain accountability but explore other methods of risk assessment. <br /><br />Kind regardsJosephhttps://www.blogger.com/profile/00017694474654816058noreply@blogger.comtag:blogger.com,1999:blog-18505975.post-86916822142902353002012-12-01T01:02:37.281-08:002012-12-01T01:02:37.281-08:00Dear Matt
Thank you for explanation
In essence t...Dear Matt<br /><br />Thank you for explanation<br /><br />In essence the FDA practises defensive medicine in order not to be sued<br /><br />If potentially useful medicines are not reaching patients because of fear of litigation then there neeeds to be a change to the system to protect the FDA from lawsuits but at the same time still holding them accountable for their decisions<br /><br />Kind regards<br /><br />Joseph Josephhttps://www.blogger.com/profile/00017694474654816058noreply@blogger.comtag:blogger.com,1999:blog-18505975.post-34870563053380850322008-04-05T09:42:00.000-07:002008-04-05T09:42:00.000-07:00Thank you for pointing me to the JAMA article. Pe...Thank you for pointing me to the JAMA article. Perhaps after reading it my comments will need further revision. <BR/><BR/>But, you are correct. In real experiments with pharmaceuticals, I'm sure an actual hypothesis is much more technical and specific than 'drug is safe' etc. <BR/><BR/>The purpose of Ho and Ha in this example is not to be realistic , but to serve as a behavioral model that abstracts from reality to focus on the importance of incentives and how they affect decision making. This example where a hypothesis is specified as 'drug is safe' is a generalization used proliferantly throughout economic literature. <BR/><BR/>However, I think your comment brings up a good point. Maybe, to be somewhat more precise, and still maintain the models explanatory power conveyed by abstraction, we should clarify what we mean by 'drug is safe'. <BR/><BR/>Perhaps it should be noted that this implies that given the pelthora of biochemical and statistical tests associated with drug approval, a decision maker claims that the 'drug is candidate for release' or something like that. <BR/><BR/>Sometimes it may be the case that economists, as modeling fanatics, and going for big picture applications, get carried away and aren't explicit enough about what their assumptions are. More congnizance about that issue, and the fact that their audience may often include non-economists would go far in winning acceptance for models they present for policy applications.Matt Bogardhttps://www.blogger.com/profile/10510725993509264716noreply@blogger.comtag:blogger.com,1999:blog-18505975.post-3978393076121043142008-03-28T08:33:00.000-07:002008-03-28T08:33:00.000-07:00your Ho and Ha as stated are not realistic. [wher...your Ho and Ha as stated are <BR/>not realistic. <BR/>[where has the FDA stated an alternative hypothesis<BR/> 'drug is safe' ?]<BR/><BR/>but the general issue you are trying to get at _is_ very relevant-> see eg Piaggio et al.<BR/>JAMA. 2006 Mar 8;295(10):1152-60.Anonymousnoreply@blogger.com